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mouse anti human p53 do 1 primary antibody  (Santa Cruz Biotechnology)


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    Structured Review

    Santa Cruz Biotechnology mouse anti human p53 do 1 primary antibody
    ( A ) Gene ontology enrichment analysis of epithelial clusters (Epi1–Epi5, EMT) using upregulated genes (Log2(FC) > 0.5, adj. p-value > 0.05). Top: Bubble plots showing significant enriched pathways and biological processes, with color intensity representing q-values and bubble size representing the gene ratio (%). Bottom: Schematic representation of the top expressed genes and associated pathways for each cluster. ( B ) Spatial transcriptomic mapping of representative biological pathways across vascularized spheroid sections, illustrating enrichment of negative ferroptosis regulation, G2/M checkpoint activity, IFN-α response, <t>p53</t> signaling, and EMT programs. ( C ) Schematic of spheroid cultured for 7 days in 3D within the hydrogel region of the OrganiX TM inserts (left), and representative confocal images of C and CSEM spheroid models showing immunofluorescence validation of <t>p53</t> <t>expression</t> (green: PANC-1; red: p53; blue: DRAQ7 nuclear stain). Scale bar: 200µm. Schematics created in BioRender.com. ( D ) Spatial visualization of p53 transcriptional signature in the CSEM spheroids. Color scale indicates module score for the mentioned gene set. ( E ) Spatial distribution of gene expression for the most significantly enriched biological process of each epithelial cell cluster in vascularized quadri-culture spheroids. Color scale indicates module score for the mentioned gene set.
    Mouse Anti Human P53 Do 1 Primary Antibody, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 96/100, based on 15818 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/mouse+anti+human+p53+do+1+primary+antibody/p53+Antibody/bio_rxiv__64898__2026__03__05__709702-293-5-11
    Average 96 stars, based on 15818 article reviews
    mouse anti human p53 do 1 primary antibody - by Bioz Stars, 2026-10
    96/100 stars

    Images

    1) Product Images from "Multi-omics and functional analysis of a bioengineered vascularized pancreatic cancer model reveal an immunosuppressive and therapy-resistant niche"

    Article Title: Multi-omics and functional analysis of a bioengineered vascularized pancreatic cancer model reveal an immunosuppressive and therapy-resistant niche

    Journal: bioRxiv

    doi: 10.64898/2026.03.05.709702

    ( A ) Gene ontology enrichment analysis of epithelial clusters (Epi1–Epi5, EMT) using upregulated genes (Log2(FC) > 0.5, adj. p-value > 0.05). Top: Bubble plots showing significant enriched pathways and biological processes, with color intensity representing q-values and bubble size representing the gene ratio (%). Bottom: Schematic representation of the top expressed genes and associated pathways for each cluster. ( B ) Spatial transcriptomic mapping of representative biological pathways across vascularized spheroid sections, illustrating enrichment of negative ferroptosis regulation, G2/M checkpoint activity, IFN-α response, p53 signaling, and EMT programs. ( C ) Schematic of spheroid cultured for 7 days in 3D within the hydrogel region of the OrganiX TM inserts (left), and representative confocal images of C and CSEM spheroid models showing immunofluorescence validation of p53 expression (green: PANC-1; red: p53; blue: DRAQ7 nuclear stain). Scale bar: 200µm. Schematics created in BioRender.com. ( D ) Spatial visualization of p53 transcriptional signature in the CSEM spheroids. Color scale indicates module score for the mentioned gene set. ( E ) Spatial distribution of gene expression for the most significantly enriched biological process of each epithelial cell cluster in vascularized quadri-culture spheroids. Color scale indicates module score for the mentioned gene set.
    Figure Legend Snippet: ( A ) Gene ontology enrichment analysis of epithelial clusters (Epi1–Epi5, EMT) using upregulated genes (Log2(FC) > 0.5, adj. p-value > 0.05). Top: Bubble plots showing significant enriched pathways and biological processes, with color intensity representing q-values and bubble size representing the gene ratio (%). Bottom: Schematic representation of the top expressed genes and associated pathways for each cluster. ( B ) Spatial transcriptomic mapping of representative biological pathways across vascularized spheroid sections, illustrating enrichment of negative ferroptosis regulation, G2/M checkpoint activity, IFN-α response, p53 signaling, and EMT programs. ( C ) Schematic of spheroid cultured for 7 days in 3D within the hydrogel region of the OrganiX TM inserts (left), and representative confocal images of C and CSEM spheroid models showing immunofluorescence validation of p53 expression (green: PANC-1; red: p53; blue: DRAQ7 nuclear stain). Scale bar: 200µm. Schematics created in BioRender.com. ( D ) Spatial visualization of p53 transcriptional signature in the CSEM spheroids. Color scale indicates module score for the mentioned gene set. ( E ) Spatial distribution of gene expression for the most significantly enriched biological process of each epithelial cell cluster in vascularized quadri-culture spheroids. Color scale indicates module score for the mentioned gene set.

    Techniques Used: Activity Assay, Cell Culture, Immunofluorescence, Biomarker Discovery, Expressing, Staining, Gene Expression

    Related Articles

    Incubation:

    Article Title: Multi-omics and functional analysis of a bioengineered vascularized pancreatic cancer model reveal an immunosuppressive and therapy-resistant niche
    Article Snippet: .. Upon washing, overnight incubation with mouse anti-human p53 (DO-1) primary antibody (Santa Cruz Biotechnology, Dallas, TX, USA, Cat. no. SC-126) in 1% BSA PBS was performed at 40C. ..



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    mouse anti human p53 do 1 primary antibody  (Santa Cruz Biotechnology)
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    Santa Cruz Biotechnology mouse anti human p53 do 1 primary antibody
    ( A ) Gene ontology enrichment analysis of epithelial clusters (Epi1–Epi5, EMT) using upregulated genes (Log2(FC) > 0.5, adj. p-value > 0.05). Top: Bubble plots showing significant enriched pathways and biological processes, with color intensity representing q-values and bubble size representing the gene ratio (%). Bottom: Schematic representation of the top expressed genes and associated pathways for each cluster. ( B ) Spatial transcriptomic mapping of representative biological pathways across vascularized spheroid sections, illustrating enrichment of negative ferroptosis regulation, G2/M checkpoint activity, IFN-α response, <t>p53</t> signaling, and EMT programs. ( C ) Schematic of spheroid cultured for 7 days in 3D within the hydrogel region of the OrganiX TM inserts (left), and representative confocal images of C and CSEM spheroid models showing immunofluorescence validation of <t>p53</t> <t>expression</t> (green: PANC-1; red: p53; blue: DRAQ7 nuclear stain). Scale bar: 200µm. Schematics created in BioRender.com. ( D ) Spatial visualization of p53 transcriptional signature in the CSEM spheroids. Color scale indicates module score for the mentioned gene set. ( E ) Spatial distribution of gene expression for the most significantly enriched biological process of each epithelial cell cluster in vascularized quadri-culture spheroids. Color scale indicates module score for the mentioned gene set.
    Mouse Anti Human P53 Do 1 Primary Antibody, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/mouse+anti+human+p53+do+1+primary+antibody/p53+Antibody/bio_rxiv__64898__2026__03__05__709702-293-5-11
    Average 96 stars, based on 1 article reviews
    mouse anti human p53 do 1 primary antibody - by Bioz Stars, 2026-10
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    primary mouse anti-human wild-type p53 monoclonal antibody do-1  (MBL Life science)
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    ( A ) Gene ontology enrichment analysis of epithelial clusters (Epi1–Epi5, EMT) using upregulated genes (Log2(FC) > 0.5, adj. p-value > 0.05). Top: Bubble plots showing significant enriched pathways and biological processes, with color intensity representing q-values and bubble size representing the gene ratio (%). Bottom: Schematic representation of the top expressed genes and associated pathways for each cluster. ( B ) Spatial transcriptomic mapping of representative biological pathways across vascularized spheroid sections, illustrating enrichment of negative ferroptosis regulation, G2/M checkpoint activity, IFN-α response, <t>p53</t> signaling, and EMT programs. ( C ) Schematic of spheroid cultured for 7 days in 3D within the hydrogel region of the OrganiX TM inserts (left), and representative confocal images of C and CSEM spheroid models showing immunofluorescence validation of <t>p53</t> <t>expression</t> (green: PANC-1; red: p53; blue: DRAQ7 nuclear stain). Scale bar: 200µm. Schematics created in BioRender.com. ( D ) Spatial visualization of p53 transcriptional signature in the CSEM spheroids. Color scale indicates module score for the mentioned gene set. ( E ) Spatial distribution of gene expression for the most significantly enriched biological process of each epithelial cell cluster in vascularized quadri-culture spheroids. Color scale indicates module score for the mentioned gene set.
    Primary Mouse Anti Human Wild Type P53 Monoclonal Antibody Do 1, supplied by MBL Life science, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Image Search Results


    ( A ) Gene ontology enrichment analysis of epithelial clusters (Epi1–Epi5, EMT) using upregulated genes (Log2(FC) > 0.5, adj. p-value > 0.05). Top: Bubble plots showing significant enriched pathways and biological processes, with color intensity representing q-values and bubble size representing the gene ratio (%). Bottom: Schematic representation of the top expressed genes and associated pathways for each cluster. ( B ) Spatial transcriptomic mapping of representative biological pathways across vascularized spheroid sections, illustrating enrichment of negative ferroptosis regulation, G2/M checkpoint activity, IFN-α response, p53 signaling, and EMT programs. ( C ) Schematic of spheroid cultured for 7 days in 3D within the hydrogel region of the OrganiX TM inserts (left), and representative confocal images of C and CSEM spheroid models showing immunofluorescence validation of p53 expression (green: PANC-1; red: p53; blue: DRAQ7 nuclear stain). Scale bar: 200µm. Schematics created in BioRender.com. ( D ) Spatial visualization of p53 transcriptional signature in the CSEM spheroids. Color scale indicates module score for the mentioned gene set. ( E ) Spatial distribution of gene expression for the most significantly enriched biological process of each epithelial cell cluster in vascularized quadri-culture spheroids. Color scale indicates module score for the mentioned gene set.

    Journal: bioRxiv

    Article Title: Multi-omics and functional analysis of a bioengineered vascularized pancreatic cancer model reveal an immunosuppressive and therapy-resistant niche

    doi: 10.64898/2026.03.05.709702

    Figure Lengend Snippet: ( A ) Gene ontology enrichment analysis of epithelial clusters (Epi1–Epi5, EMT) using upregulated genes (Log2(FC) > 0.5, adj. p-value > 0.05). Top: Bubble plots showing significant enriched pathways and biological processes, with color intensity representing q-values and bubble size representing the gene ratio (%). Bottom: Schematic representation of the top expressed genes and associated pathways for each cluster. ( B ) Spatial transcriptomic mapping of representative biological pathways across vascularized spheroid sections, illustrating enrichment of negative ferroptosis regulation, G2/M checkpoint activity, IFN-α response, p53 signaling, and EMT programs. ( C ) Schematic of spheroid cultured for 7 days in 3D within the hydrogel region of the OrganiX TM inserts (left), and representative confocal images of C and CSEM spheroid models showing immunofluorescence validation of p53 expression (green: PANC-1; red: p53; blue: DRAQ7 nuclear stain). Scale bar: 200µm. Schematics created in BioRender.com. ( D ) Spatial visualization of p53 transcriptional signature in the CSEM spheroids. Color scale indicates module score for the mentioned gene set. ( E ) Spatial distribution of gene expression for the most significantly enriched biological process of each epithelial cell cluster in vascularized quadri-culture spheroids. Color scale indicates module score for the mentioned gene set.

    Article Snippet: Upon washing, overnight incubation with mouse anti-human p53 (DO-1) primary antibody (Santa Cruz Biotechnology, Dallas, TX, USA, Cat. no. SC-126) in 1% BSA PBS was performed at 40C.

    Techniques: Activity Assay, Cell Culture, Immunofluorescence, Biomarker Discovery, Expressing, Staining, Gene Expression